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pentobarbital will lessen the level or outcome of indinavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.pentobarbital will minimize the extent or effect of dienogest/estradiol valerate by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Gals must not choose estradiol valerate/dienogest as the